Image depicting Drug Shortages Update.

Drug Shortages Update: April 2022

This week we are once again providing an update on the most recent drug shortages.

Drug shortages currently remain at over 100 different medications, with the Food and Drug Administration (FDA) noting 120 products as being unavailable. Some of these shortages are short term, or limited availability, while others are completely unavailable with unknown release dates.

As noted above, the current list stands at 120 products, which is up four from our last update in February. Below we have two separate lists of medications in short supply. The first list covers the most commonly used medications in ambulatory surgery centers, while the second addresses medications commonly used long-term care facilities.

Common ASC medications in short supply:

  • Acetazolamide Injection
  • Atropine Sulfate Injection
  • Azithromycin (Azasite) Ophthalmic Solution 1%
  • Bacteriostatic 0.9% Sodium Chloride Injection
  • Bacteriostatic Water for Injection
  • Bupivacaine Hydrochloride and Epinephrine Injection
  • Bupivacaine Hydrochloride Injection
  • Calcium Gluconate Injection
  • Cefazolin Injection
  • Cefotaxime Sodium Injection
  • Chloroprocaine Hydrochloride Injection
  • Cyclopentolate Ophthalmic Solution
  • Dexamethasone Sodium Phosphate Injection
  • Dexmedetomidine Injection
  • Dextrose 10% Injection
  • Dextrose 25% Injection
  • Dextrose 5% Injection
  • Dextrose 50% Injection
  • Digoxin Injection
  • Diltiazem Hydrochloride Injection
  • Dobutamine Hydrochloride Injection
  • Dopamine Hydrochloride Injection
  • Epinephrine Injection, 0.1 mg/mL
  • Epinephrine Injection, Auto-Injector
  • Fentanyl Citrate (Sublimaze) Injection
  • Furosemide Injection
  • Gentamicin Sulfate Injection
  • Heparin Sodium and Sodium Chloride 0.9% Injection
  • Hydrocortisone Tablets
  • Hydromorphone Hydrochloride Injection
  • Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert
  • Ketamine Injection
  • Ketorolac Tromethamine Injection
  • Lidocaine Hydrochloride (Xylocaine) Injection
  • Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine
  • Lipid Injection
  • Lorazepam Injection
  • Mannitol Injection
  • Mepivacaine Hydrochloride Injection
  • Methylprednisolone Acetate Injection
  • Midazolam Injection
  • Morphine Sulfate Injection
  • Ondansetron Hydrochloride Injection
  • Physostigmine Salicylate Injection
  • Potassium Acetate Injection
  • Potassium Chloride Concentrate Injection
  • Promethazine (Phenergan) Injection
  • Propofol Injectable Emulsion
  • Protamine Sulfate Injection
  • Ropivacaine Hydrochloride Injection
  • Sodium Acetate Injection
  • Sodium Bicarbonate Injection
  • Sodium Chloride 0.9% Injection Bags
  • Sodium Chloride 23.4% Injection
  • Sodium Chloride Injection USP, 0.9% Vials and Syringes
  • Sodium Phosphates Injection
  • Sterile Water for Injection
  • Triamcinolone Acetonide Injectable Suspension
  • Triamcinolone Hexacetonide Injectable suspension
  • Valproate Sodium Injection
  • Vecuronium Bromide for Injection

Common LTC medications in short supply:

  • Amino Acids
  • Amoxapine Tablets
  • Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets
  • Amphetamine Oral Suspension, Extended Release
  • Azithromycin (Azasite) Ophthalmic Solution 1%
  • Bacteriostatic 0.9% Sodium Chloride Injection
  • Bacteriostatic Water for Injection
  • Belatacept (Nulojix) Lyophilized Powder for Injection
  • Bupivacaine Hydrochloride and Epinephrine Injection
  • Bupivacaine Hydrochloride Injection
  • Calcium Gluconate Injection
  • Cefazolin Injection
  • Cefixime Oral Capsules
  • Cefotaxime Sodium Injection
  • Cefotetan Disodium Injection
  • Chlordiazepoxide Hydrochloride Capsules
  • Cortisone Acetate Tablets
  • Cyclopentolate Ophthalmic Solution
  • Cysteamine Hydrochloride Ophthalmic Solution
  • Desmopressin Acetate Nasal Spray
  • Dexamethasone Sodium Phosphate Injection
  • Dextrose 10% Injection
  • Dextrose 25% Injection
  • Dextrose 5% Injection
  • Dextrose 50% Injection
  • Diflunisal Tablets
  • Digoxin Injection
  • Diltiazem Hydrochloride Injection
  • Disopyramide Phosphate (Norpace) Capsules
  • Dobutamine Hydrochloride Injection
  • Dopamine Hydrochloride Injection
  • Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution
  • Epinephrine Injection, Auto-Injector
  • Fluvoxamine ER Capsules
  • Gemifloxacin Mesylate (Factive) Tablets
  • Gentamicin Sulfate Injection
  • Guanfacine Hydrochloride Tablets
  • Heparin Sodium and Sodium Chloride 0.9% Injection
  • Hydrocortisone Tablets
  • Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert
  • Imipenem and Cilastatin for Injection
  • Isoniazid Injection
  • Ketoprofen Capsules
  • Leuprolide Acetate Injection
  • Lidocaine Hydrochloride (Xylocaine) Injection
  • Lorazepam Injection
  • Mannitol Injection
  • Methyldopa Tablets
  • Methylprednisolone Acetate Injection
  • Morphine Sulfate Injection
  • Nefazodone Hydrochloride Tablets
  • Nizatidine Capsules
  • Ondansetron Hydrochloride Injection
  • Pantoprazole Sodium for Injection
  • Rifampin Capsules
  • Rifapentine Tablets
  • Sodium Chloride 0.9% Injection Bags
  • Sodium Chloride Injection USP, 0.9% Vials and Syringes
  • Sterile Water for Injection
  • Sulfasalazine Tablets
  • Tacrolimus Capsules
  • Thiothixene Capsules
  • Tocilizumab Injection
  • Trimethobenzamide Hydrochloride Capsules
  • Varenicline Tartrate (Chantix) Tablets

Steps you can take:

The solution to each shortage is going to differ by the medication involved and the available alternatives. In a previous post titled “Ten Steps to Dealing with Drug Shortages”, I discussed ways to deal with shortages.

If you are currently struggling with a particular shortage, work with your pharmacy consultant to come up with creative ways to work around it. This requires planning and expertise. Some solutions may seem obvious and easy, but they could be dangerous to patient safety and often not compliant with licensing or accreditation standards. If you have questions about a current shortage, or how to set up a compliant system, don’t hesitate to reach out to us.


The Consultant Pharmacists at OctariusRx provide guidance on safe medication management, survey readiness and cost savings to ambulatory healthcare facilities/surgery centerssenior care facilities and pharmacies. We also help individual patients optimize their medications to improve their quality of life and save money. Contact us for assistance.


Any health, medical or drug information on the Web Site is for informational purposes only. This information is not intended to be used, and you should not use it, as a substitute for obtaining professional healthcare advice, diagnosis or treatment. You should always seek the advice of your doctor, a pharmacist or other qualified healthcare provider for professional healthcare advice, diagnosis or treatment for any medical condition.