Although the debate about whether to use intracameral antibiotics marches on, what is not in question is our collective desire to give patients the best and safest possible outcome. For the facilities contemplating intracameral antibiotics, which drug should you use? What is the best way to prepare it or obtain it? These are all valid questions you should ask. Use the expertise of your consultant pharmacist to help navigate these difficult, but extremely important decisions. Making the right choice will increase patient safety and reduce risks. The wrong decision could be devastating.

Is your facility using Intracameral Antibiotics?

Although the debate about whether to use intracameral antibiotics marches on, what is not in question is our collective desire to give patients the best and safest possible outcome.  For the facilities contemplating intracameral antibiotics, which drug should you use?  What is the best way to prepare it or obtain it?  These are all valid questions you should ask.

Use the expertise of your consultant pharmacist to help navigate these difficult, but extremely important decisions.  Making the right choice will increase patient safety and reduce risks.  The wrong decision could be devastating.

Although practice patterns vary throughout the world, in the United States, the most common method of prophylaxis against endophthalmitis is still topical antibiotics.  In other parts of the world, such as Europe, intracameral antibiotics are favored.   In the facilities we serve and for the ones who choose to use the intracameral route, moxifloxacin is often the preferred drug, although there is no consensus on which drug is best.

The use of moxifloxacin in this manner is considered off-label and requires a bit of due diligence to ensure the facility is taking all the appropriate steps to improve patient safety and reduce risks.  Since moxifloxacin solution for intracameral injection is not commercially available, are you preparing it, or obtaining it from a compounding pharmacy?  Do they specialize in ophthalmic preparations? If you’re using a compounding pharmacy, have you done your homework to make sure you’re working with a facility that is state licensed, 503B registered with the FDA and in good standing?  This can be an overwhelming and tedious process, but your consultant pharmacist can help.

There are many moving parts in the decision to use intracameral antibiotics.  Work with your consultant pharmacist to ensure you feel confident in the process your facility is following.  If you are contemplating intracameral antibiotics, or currently using them but want to have a third party review your process or if you just have questions on this topic, please contact us.


The Consultant Pharmacists at OctariusRx provide guidance on safe medication management, survey readiness and cost savings to ambulatory healthcare facilities/surgery centerssenior care facilities and pharmacies  We also help individual patients optimize their medications to improve their quality of life and save money. Contact us for assistance.


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